intermediatePTSDtrauma-focused therapySSRISNRIprolonged exposurecognitive processing therapytreatment guidelines
A 29-year-old female veteran presents with a 14-month history of intrusive memories, hypervigilance, nightmares, emotional numbing, and avoidance of trauma-related stimuli following combat exposure. She meets DSM-5 criteria for posttraumatic stress disorder. She has no prior psychiatric treatment and no comorbid substance use disorder. Her PCL-5 score is 52, indicating significant symptom severity. She expresses willingness to engage in both medication and psychotherapy. Which of the following best describes the evidence-based approach to first-line treatment planning for this patient?