Clinical Case Library

Practice the calls that make students freeze.

Work through realistic PMHNP cases before you are the one sitting across from the patient. Each case forces a decision, explains the trap, and shows the reasoning behind the best next move.

Try free caseUnlock full library
How a case works

You do not just answer. You learn why the answer changes.

Patient
Start with a realistic presentation: history, symptoms, risk, medications, and missing information.
Decision
Choose from several plausible next steps, not cartoonishly wrong answers.
Debrief
See why the best choice fits and why the tempting alternatives break down.
75+
interactive cases
7
clinical categories
Find the right case

Search by diagnosis, medication, principle, or clinical problem.

Look up the topic you are trying to understand, or browse the full library by category below.

Featured cases

Start with a case that feels uncomfortably real.

These are not one-step quiz stems. They are clinical scenarios with ambiguity, tradeoffs, and answer choices that can look reasonable if you miss the key detail.

intermediate ยท 25 min

ADHD + Anxiety: Which Do You Treat First?

A 29-year-old software engineer presents with well-established ADHD-inattentive type and co-occurring generalized anxiety disorder, raising the question of which condition to treat first and how to navigate medication choices when treatments for one may complicate the other.

Open case โ†’
intermediate ยท 30 min

ADHD vs Burnout: When the High Performer Stops Performing

A 39-year-old corporate attorney and law firm partner presents with 6 months of progressive concentration difficulties, exhaustion, emotional flatness, and a sense that her brain 'stopped working.' Her PCP referred her after a positive ADHD screen she requested based on social media content. Navigate the increasingly common clinical challenge of distinguishing late-unmasked ADHD from occupational burnout and depression with prominent cognitive symptoms.

Open case โ†’
intermediate ยท 25 min

Akathisia: The Side Effect That Looks Like the Disease

A 52-year-old man with treatment-resistant MDD developed intense restlessness 3 weeks after aripiprazole augmentation. His previous provider misinterpreted the symptoms as worsening anxiety and increased the dose, making everything worse. Learn to recognize akathisia, avoid the catastrophic error of escalating the offending agent, and manage this common and dangerous side effect.

Open case โ†’
advanced ยท 30 min

Anorexia Nervosa: When the Body Is Failing

A 22-year-old college student presents with a BMI of 14.8, bradycardia, and electrolyte abnormalities after months of progressive restriction. This case explores the medical urgency of severe anorexia nervosa, refeeding syndrome risk, and why there are no FDA-approved medications for this disorder.

Open case โ†’
intermediate ยท 25 min

Antidepressant Discontinuation Syndrome

A 41-year-old man abruptly stopped venlafaxine 225mg after two years of successful MDD treatment and now presents with 'brain zaps,' dizziness, nausea, and emotional lability, raising the question of whether this is a true depressive relapse or antidepressant discontinuation syndrome.

Open case โ†’
advanced ยท 30 min

Bipolar II. Maintenance Phase Decisions

A 42-year-old school psychologist with bipolar II disorder, stable for 18 months on lamotrigine and quetiapine, requests medication simplification due to weight gain, morning grogginess, and emerging metabolic concerns. The clinician must weigh the legitimate burden of long-term side effects against the risk of destabilizing a patient who is doing well, navigating a clinical space where guidelines offer little guidance and the art of psychiatry matters most.

Open case โ†’
Try before you subscribe

Take one case for free.

Work through the first case and see whether the reasoning style helps. If it does, the full library is there when you need more reps. Pair it with our 991+ free practice questions for board prep.

Try the free case
PMHNP Clinical Case Studies | PMHNP Helper