Questions/Ethics & Legal/Q7 of 27
intermediateautonomybeneficencetreatment refusalclozapineinformed refusalethics
A 58-year-old woman with schizoaffective disorder has been stable on clozapine for 5 years. She presents for her regular appointment and announces she wants to stop clozapine because she read online that it causes weight gain and metabolic syndrome. She acknowledges understanding that she has been hospitalized three times prior to starting clozapine and that her previous medications were ineffective. She has full decision-making capacity. The PMHNP must navigate the tension between patient autonomy and clinical beneficence.
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