A 35-year-old man with schizophrenia has persistent auditory hallucinations and paranoid delusions despite adequate trials of risperidone (6 mg/day for 8 weeks) and aripiprazole (30 mg/day for 10 weeks) with confirmed adherence via long-acting injectable formulations. He has no history of seizures. His WBC is 6,500/mcL and ANC is 3,200/mcL. His treatment team is discussing the next pharmacological step.