advancedlithiumnephrotoxicitycreatinineeGFRbipolar disorderelderly
A 70-year-old male with well-controlled bipolar I disorder on lithium 600 mg presents with a lithium level of 0.9 mEq/L and a creatinine of 1.6 mg/dL (up from 1.1 six months ago). He is asymptomatic. What is the MOST appropriate assessment?