A 44-year-old man with well-controlled HIV on an antiretroviral regimen containing cobicistat-boosted elvitegravir presents to the PMHNP for evaluation of worsening depressive symptoms. He reports persistent low mood, anhedonia, fatigue, difficulty concentrating, and insomnia over the past six weeks. His CD4 count is 520 cells/mm3 and his viral load is undetectable. He has no prior psychiatric history but describes significant psychosocial stressors including HIV-related stigma, disclosure concerns, and anticipatory grief regarding his diagnosis. The PMHNP considers the assessment and treatment planning for this patient. Which of the following most accurately reflects the clinical considerations for psychiatric care in this population?