intermediatefunctional impairmentPHQ-9Sheehan Disability Scalebehavioral activationduloxetinemajor depressive disorderremission
A 29-year-old male with major depressive disorder has been taking duloxetine 60 mg daily for 10 weeks. His PHQ-9 score has decreased from 21 to 8, representing a 62% reduction and placing him in the mild range. However, he reports he has not returned to his previous exercise routine, continues to call in sick to work one to two times per week, has not resumed socializing with friends, and describes his daily routine as primarily watching television at home. He states the medication has helped his mood and sleep but acknowledges he is not functioning like he used to before the depressive episode. The PMHNP is evaluating overall treatment outcome. Which of the following best represents a comprehensive evaluation of this patient's treatment response?