hardECTelectroconvulsive therapytreatment-resistant depressioncognitive effectsPHQ-9MoCAretrograde amnesia
A 56-year-old female with treatment-resistant major depressive disorder underwent a course of 10 bilateral electroconvulsive therapy sessions over five weeks after failing four adequate antidepressant trials. Her pre-ECT PHQ-9 was 24 and MMSE was 28/30. After completing the acute ECT series, her PHQ-9 is 8, she reports improved sleep, appetite, and interest in activities, and she has returned to part-time work. However, she reports new difficulty remembering names of acquaintances, misplacing items more frequently, and has noticed trouble recalling events from the two weeks surrounding the ECT treatments. Her current MMSE is 27/30 and MoCA is 24/30. She expresses concern about whether her memory will return to normal. The PMHNP is evaluating the treatment outcomes and cognitive effects. Which of the following best represents the appropriate evaluation?