Prolactin level, as risperidone is among the highest prolactin-elevating SGAs and is the most likely cause.
Risperidone is among the highest prolactin-elevating SGAs due to its potent D2 antagonism and poor blood-brain barrier penetration at the pituitary. A prolactin level confirms the diagnosis and quantifies the severity. If prolactin is markedly elevated (>100-200 ng/mL), pituitary imaging may be warranted to rule out a prolactinoma — though medication-induced elevation is far more likely in this context. These findings inform subsequent treatment planning decisions.