Antidepressants · SSRIs

Fluoxetine

Brand: Prozac, Prozac Weekly (delayed-release 90mg), Sarafem (for PMDD)

Selective serotonin reuptake inhibitor (SSRI)

9 cards

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Card Topics

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All Cards

1.How long must you wait after stopping fluoxetine before starting an MAOI? Why is this different from other SSRIs?

2.Fluoxetine CYP profile: which enzyme, and name 3 clinically dangerous substrate interactions.

3.Why does fluoxetine essentially never cause discontinuation syndrome?

4.Fluoxetine dosing: depression vs OCD vs bulimia.

5.Which SSRI has the strongest pediatric evidence base, and for which indications?

6.A breast cancer patient on tamoxifen needs an SSRI. Which SSRIs must you avoid and why?

7.Name the only SSRI with FDA approval for bulimia nervosa.

8.What is the SSRI/SNRI black box warning, and how does monitoring differ by age?

9.SSRI-induced sexual dysfunction: how common, and what are the management strategies?

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