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← SNRIs
Antidepressants · SNRIs

Duloxetine

Brand: Cymbalta

Serotonin-norepinephrine reuptake inhibitor (SNRI)

7 cards

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Card Topics

dosing (2)monitoring (1)trap (2)interaction (2)

All Cards

1.Name duloxetine's 3 FDA-approved pain indications (beyond MDD and GAD).
2.What lab should you check before starting duloxetine that most antidepressants do NOT require?
3.Depressed patient with diabetic neuropathy. Why is an SSRI the wrong answer?
4.Duloxetine is a CYP1A2 substrate. What common habit affects its levels?
5.Duloxetine is a moderate CYP2D6 inhibitor. Name 2 clinically important consequences.
6.Patient on duloxetine develops ALT 180, AST 145, and jaundice. Next step?
7.What is the standard therapeutic dose of duloxetine?

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