A 45-year-old male with alcohol use disorder presents requesting naltrexone to support his sobriety. He has been abstinent from alcohol for 4 weeks and is highly motivated. During the medication history review, he reports that he underwent a right knee arthroscopy 8 days ago and last took oxycodone 5 mg approximately 6 days ago for post-surgical pain. He denies any history of opioid use disorder and rates his current pain as 2/10 without medication. The PMHNP plans to prescribe oral naltrexone 50 mg daily. Which of the following is the most critical consideration before initiating naltrexone in this patient?